Algorithm for bone reconstruction

A deep learning model was trained on digitally reconstructed radiographs (DRRs) using the proprietary SOMA database to enable intact 3D bone reconstruction and calculate e.g. femur length and anatomical axes.

For the first time, a system was able to reconstruct the fractured area in a long bone fracture in terms of the length, axis and the rotational postition using X-rays from the knee and hip region. To this end, X-rays from the particular region from different angels are shot and a 2D to 3D transformation is performed using a X-ray reference body. Comparing the fractured leg with the unaffected contralateral side and a propriatary bone data base enables the system to align the fractured area in-between.

To run the system, a proprietary configured tablet is necessary that runs under Windows 10 at the moment. Due to the customized interfaces that are required to hook up the X-ray mechanines in the OR (C-arms) the proprietary system is needed. The system however can be intergrated into the IT system of a hospital using the FHIR-HL7 interface and export functions.

The target customers are healthcare professionals and surgeons, hospitals and trauma centers in Europe and around the world. The estimated Market volume of femoral nails in the US and Europe combined is estimated around 500 Mio $/year. . Incorrect rotation of femur fragments post-surgery can lead to high costs for hospitals and legal actions from affected patients, with a complication rate of around 20%, one of the highest in Orthopedics. A digital CAS system has the potential to revolutionize treatment by reducing complications and improving patient outcomes. It's estimated that such a solution could command a premium of at least $1,500 per case in the US, with a market volume enhancement of about $34 million annually for femoral shaft nailing alone.

No licensing is planed for this system. The integration of the system into a hospital information system or patient reporting outcome measure (PROM) system may be carried out in cooperation.